Rajendra P Parajuli, PhD
Research Associate
Gene-Environment Interaction
Basu Laboratory, McGill University
[email protected]
Research Associate
Gene-Environment Interaction
Basu Laboratory, McGill University
[email protected]
A) Educational Background
· PhD. 2010. Health Science, University of Tokyo, Japan
· MS. 2007. Health Science, University of Tokyo, Japan
· MA. 2005. Rural Development, Tribhuvan University, Nepal
· MS. 2003. Parasitology, Tribhuvan University, Nepal
· MS. 2007. Health Science, University of Tokyo, Japan
· MA. 2005. Rural Development, Tribhuvan University, Nepal
· MS. 2003. Parasitology, Tribhuvan University, Nepal
B) Research Interests and Current Projects
Genetic Epidemiology, Gene-Environment Interaction and Eco-Health
Specifically, I want to know the effect of genetic polymorphism in toxic chemical (Heavy metals as well as pesticides) metabolism in body to see their modifying effect in health outcomes like cardiovascular disease (CVD) or Neurodevelopmental outcomes (IQ), etc.
Specifically, I want to know the effect of genetic polymorphism in toxic chemical (Heavy metals as well as pesticides) metabolism in body to see their modifying effect in health outcomes like cardiovascular disease (CVD) or Neurodevelopmental outcomes (IQ), etc.
C) Honours and Awards
- Asian Development Bank Japan Scholarship (ADB-JSP) Scholarship as a graduate student in University of Tokyo. Mar. 2005 to Mar. 2007.
- University of Tokyo Fellowship (Todai Fellowship) as a graduate student in University of Tokyo. Mar. 2007 to Mar. 2010.
- Foreign Researcher Award, University of Tokyo, International office of Academic Affairs (IOAA), Japan, 19th Feb 2009
D) Previous Research and Professional Experience
- Effects of in-utero lead, arsenic and zinc & Postnatal Growth Environment on Neurodevelopment in Nepali Children: a Birth Cohort Study
- Environmental Research in Rural Asia (ENVRERA) project: To examine the effects of agriculture land use change on the wellbeing of people
- Mechanism of Sex-difference and its toxicological significance in toxic manifestation of inorganic Arsenic: Nepal Arsenic Project
Research Associate, (2014 Oct –Current) Environmental Health Sciences Lab, McGill University, Natural Resource Science, Montreal, Quebec, Canada.
Associate, (2014 April – Current). International Institute for Child Rights and Development (IICRD), PO Box 8646 Victoria Main, Victoria, British Columbia, Canada
Postdoctoral Fellow, (April 2013 to March 2014): Department of Human Ecology, University of Tokyo, Japan
Research Fellow, (April 2011 – March 2013). Department of Social Medicine, National Research Institute for Child Health and Development, Tokyo, Jap
Postdoctoral Fellow, (June 2010 to March 2011) Department of Human Ecology, University of Tokyo, Japan
E) Publications and Presentations
- Kishi R, Zhang JJ, Ha EH, Chen PC, Tian Y, Xia Y, Tsuchiya KJ, Nakai K, Kim S, Hong SJ, Hong YC, Lee JR, Mohamed HJBJ, Parajuli RP, Adair LS, Chong YS, Guo YL, Wang SL, Nishijo M, Kido T, Tai PT, Nandasena S. (2016) Birth Cohort Consortium of Asia (BiCCA)-Current and Future Perspectives, Epidemiology, Accepted
- Thomas DB, Basu N, Martinez-Mier EA, Sánchez BN, Zhang Z, Liu Y, Parajuli RP, Peterson K, Mercado-Garcia A, Bashash M, Hernández-Avila M, Hu H, Téllez-Rojo MM. (2016) Urinary and plasma fluoride levels in pregnant women from Mexico City. Environmental Research, Volumn 150, Pags 489-95. PubMed
- Fillman T, Furusawa H, Fook SNC, Parajuli RP, and Watanabe C. (2016) Association of Cadmium and Arsenic Exposure with Salivary Telomere Length in Adolescents in Terai, Nepal. Environmental Research Volume 149, Pages 8–14 [LINK]
- Parajuli RP, Goodrich JM, Chou HN, Gruninger SE, Dolinoy DC, Franzblau A and Basu N. (2015) Genetic Polymorphisms are Associated with Hair, Blood, and Urine Mercury Levels in the American Dental Association (ADA) Study Participants. Environmental Research PubMed
- Parajuli RP, Umezaki M, Fujiwara T, & Watanabe C. (2015) Association of Cord Blood Levels of Lead, Arsenic, and Zinc and Home Environment with Children Neurodevelopment at 36 Months Living in Chitwan Valley, Nepal. PLoS ONE 10(3): e0120992. doi:10.1371/journal.pone.0120992 PubMed
- Parajuli RP, Fujiwara T, Umezaki M, & Watanabe C. (2015) Home Environment and Cord Blood Levels of Lead, Arsenic, and Zinc on Neurodevelopment of 24 months Children Living in Chitwan valley, Nepal, Journal of Trace Elements in Medicine and Biology 29: 315–320 doi:10.1016/j.jtemb.2014.08.006, PubMed
- Parajuli RP, Fujiwara T, Umezaki M, Furusawa H, & Watanabe C. (2014). Letter in response to Dr. José G. Dórea Letter “Chemical mixtures, maternal exposure and infant neurodevelopment: did we miss positive (breastfeeding) and negative (mercury) confounders?” Neuro-toxicology and Teratology, 45, 94-94, PubMed
- Parajuli RP, Fujiwara T, Umezaki M, & Watanabe C. (2014). Impact of Socioeconomic Position on the Neurodevelopment of Young Children from Birth to 36 Months of Age: A Birth Cohort Study in Chitwan Valley, Nepal BMC Pediatrics 14:56. DOI:10.1186/1471-2431-14-56, PubMed
- Parajuli,RP, Umezaki M, Fujiwara T, Konishi S, Takane E, Maharjan M, Tachibana K, Jiang HW, Pahari K, and Watanabe C. (2014). Prevalence and risk factors of Soil-transmitted helminth infection in Nepal. Transactions of the Royal Society of Tropical Medicine and Hygiene 108 (4): 228–236. DOI: 10.1093/trstmh/tru013, PubMed
- Konishi S, Parajuli RP, Takane E, Maharjan M, Jiang H, Pahari K, Inoue Y, Umezaki M, and Watanabe C. (2014). Significant sex difference in the association between C-reactive protein concentration and anthropometry among 13-19-years-olds, but not 6-12-years-olds in Nepal. American Journal of Physical Anthropology DOI: 10.1002/ajpa.22470, PubMed
- Parajuli RP, Fujiwara T, Umezaki M, Furusawa H, & Watanabe C. (2014). Home Environment and Prenatal exposure to Lead, Arsenic and Zinc on the Neurodevelopment of Six-month-old Infants Living in Chitwan Valley, Nepal Neuro-toxicology and Teratology 41 89- 95. DOI 10.1016/j.ntt.2013.12.006, PubMed
- Parajuli RP, Fujiwara T, Umezaki M, Watanabe C. (2013) Association of Cord Blood Levels of Lead, Arsenic, and Zinc with Neurodevelopmental Indicators in Newborns: A Birth Cohort Study in Chitwan Valley, Nepal. Environmental Research,121:45-51. DOI 10.1016/j.envres.2012.10.010, PubMed
- Parajuli RP, Umezaki M, and Watanabe C. (2012). Diet Among People in the Terai Region of Nepal, An Area of Micronutrient Deficiency. Journal of Biosocial Science, 44(4):401-415.DOI: 10.1017/S0021932012000065, PubMed
- Parajuli RP, Fujiwara T, Umezaki M, Furusawa H, Han SP, Watanabe C. (2012). Cord Blood Levels of Toxic and Essential Trace Elements and Their Determinants in the Terai Region of Nepal: A birth cohort study. Biological Trace Element Research, 147(1-3):75-83. DOI: 10.1007/s12011-011-9309-1, PubMed
- Konishi S, Parajuli RP, Takane E, Maharjan M, Sharma S, Tachibana K, Jiang H, Pahari K, Pandey BD, Watanabe C. (2011). Health Status of Married Women Residing Five Communities in Nepal: Unexpectedly High Prevalence of Anemia in a Well-Off Community of Kathmandu. Nepal Medical College Journal 13:1-6, PubMed
- Parajuli RP, Umezaki M, Watanabe C. (2009). Behavioral and Nutritional Factors and Geohelminth Infection among Two Ethnic Groups in the Terai Region, Nepal. American Journal of Human Biology, 21(1):98-104. DOI: 10.1002/ajhb.20825, PubMed
In Preparation
- Parajuli RP, Goodrich GM, Chan L, Lemire M, Ayotte P, Kandola K, Hegele R, and Basu N. Genetic Polymorphisms are Associated with Body Burden of Metals, Persistent Organic Pollutants (POPs) and Omega-3 Fatty Acids Levels among Inuit of ISR region in the Canadian Arctic
- Parajuli RP, Goodrich GM, Chan L, Lemire M, Ayotte P, Kandola K, Hegele R, and Basu N. Genetic Polymorphisms are Associated with Body Burden of Metals, Persistent Organic Pollutants (POPs) and Omega-3 Fatty Acids Levels among Inuit of Nunavik region in the Canadian Arctic
CONFERENCE PRESENTATIONS, PROCEEDINGS, AND POSTERS
- Parajuli RP, Goodrich GM, Chan L, Ayotte P, Kandola K, Hegele R, and Basu N. Genetic Polymorphisms are Associated with Body Burden of Metals, Persistent Organic Pollutants (POPs) and Omega-3 Fatty Acids Levels among Inuit in the Canadian Arctic. ISEE-2016 Rome, Italy, Aug 31-Sept 3, (Poster/Not attended) LINK
- Parajuli RP, Goodrich GM, Chan L, Ayotte P, Kandola K, Hegele R, and Basu N. Genetic Polymorphisms are Associated with Body Burden of Metals, Persistent Organic Pollutants (POPs) and Omega-3 Fatty Acids Levels among Inuit in the Canadian Arctic. ISEE-ISES AC2016 Sapporo, Hokkaido, Japan on June 26-29th, (Oral)
- Parajuli RP*, Goodrich MJ, Franzblau A, and Basu N. (2015). Genetic Polymorphisms and Hair, Blood and Urine Mercury Levels: A Gene Environment Study of Mercury in the American Dental Association (ADA) Study. 27th Conference of the International Society for Environmental Epidemiology, (ISEE), August 30 to Sept 3 2015 (São Paulo), Brazil (Oral) LINK
- Parajuli RP*, Goodrich MJ, Franzblau A, and Basu N. (2015). Genetic Polymorphisms and Hair, Blood and Urine Mercury Levels: A Gene Environment Study of Mercury in the American Dental Association (ADA) Study. Canadian Society for Epidemiology and Biostatistics CSEB 2015 CONFERENCE June 1-4 2015 (Toronto, ON), Canada LINK
- Parajuli RP*, Umezaki M, Fujiwara T, and Watanabe C. (2015). Impact of In Utero exposure of Lead (Pb), Arsenic (As) and Zinc (Zn) on the Neurodevelopment of Young Children from Birth to 36 Months of Age: A Birth Cohort Study in Chitwan Valley, Nepal. 55th Annual Meeting of the Teratology Society, on June 27 to July 1, 2015 in Montreal, Quebec, Canada.
- Parajuli RP*, Fujiwara T, Umezaki M, and Watanabe C. (2014). Home Environment and Cord Blood Levels of Lead, Arsenic, and Zinc on Neurodevelopment of 24 months Children Living in Chitwan valley, Nepal. Proceeding of 26th Annual International Society for Environmental Epidemiology (ISEE) Conference, on August 24-28th, 2014 in Seattle, Washington, USA. (Poster) LINK
- Parajuli RP*, Fujiwara T, Umezaki M, and Watanabe C. (2014). Home Environment and Cord Blood Levels of Lead, Arsenic, and Zinc on Neurodevelopment of 36 months Children Living in Chitwan valley, Nepal. Conference Proceeding of Urban Environmental Pollution 2014, on June 12 to 15, 2014. (Poster)
- Parajuli RP*, Umezaki M, and Watanabe C. (2010). Dietary Intakes of Two Minority Groups in Terai Region of Nepal. Proceeding of 35th Annual meeting of Human Biology Association: Abstract, American Journal of Human Biology. Vol.22 (2) pp. 267 (Poster)
- Parajuli RP*, Makiko S, Mashiro U, and Watanabe, C. (2008). Inter-Individual Variation in Dietary Intake and Nutritional Status in a Minority Community in Terai Region, Nepal. Proceeding of 73rd Annual meeting of The Japanese Society of Health and Human Ecology. Abstract, Vol.74. pp. 62-63. (Oral)
- Parajuli RP*, Makiko S, and Watanabe, C. (2007). Socio-economic Status, Dietary Intake, Geohelminthiasis, and their Relation with Nutritional Status of Mushar in Lowland Terai, Nepal. Proceeding of International Conference on Emerging Issues on Research and Development. Abstract, pp. 63-64. (Oral)
- Parajuli RP*, Makiko S, Mashiro U, and Watanabe, C. (2007). Dietary Intake, Geohelminthiasis, and Their Relation with Nutritional Status of Mushar in Lowland Terai, Nepal. Lifestyle-Related Diseases Prevention: The Challenge for Nutrition and Public Health. Proceeding of 39th Conference of the Asia-Pacific Academic Consortium for Public Health. Abstract, pp.111. (Oral)
- Parajuli RP*, Mishra PN, and Joshi, DD. (2004). Prevalence of Intestinal Parasites in Mushar Community of Chitwan District. Proceeding of 4th National Conference of science and Technology. Abstract, 4: 53-56. (Oral)